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1

Toxicogenomic analysis of the gene expression changes in rat liver after a 28-day oral Tripterygium wilfordii multiglycoside exposure

Yun Zhang, Zhenzhou Jiang, Mei Xue, Shuang Zhang, Yurong Wang, Luyong Zhang

Journal:

Journal of Ethnopharmacology

Year:

2012

Language:

english

File:

PDF, 821 KB

english, 2012

2

Evaluation of hepatotoxicity and cholestasis in rats treated with EtOH extract of Fructus Psoraleae

Jiaying Wang, Zhenzhou Jiang, Jinzi Ji, Yanyan Li, Mi Chen, Yurong Wang, Yun Zhang, Ting Tai, Tao Wang, Luyong Zhang

Journal:

Journal of Ethnopharmacology

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

3

Glycyrrhizin accelerates the metabolism of triptolide through induction of CYP3A in rats

Tai, Ting, Huang, Xin, Su, Yuwen, Ji, Jinzi, Su, Yijing, Jiang, Zhenzhou, Zhang, Luyong

Journal:

Journal of Ethnopharmacology

Year:

2014

Language:

english

File:

PDF, 364 KB

english, 2014

4

HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice

Shi, Dayong, Guo, Shuju, Jiang, Bo, Guo, Chao, Wang, Tao, Zhang, Luyong, Li, Jingya

Journal:

Year:

2013

Language:

english

File:

PDF, 662 KB

english, 2013

5

Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes

Li, Xiaojiaoyang, Liu, Runping, Yu, Linxi, Yuan, Zihang, Sun, Rong, Yang, Hang, Zhang, Luyong, Jiang, Zhenzhou

Journal:

Year:

2016

Language:

english

File:

PDF, 3.11 MB

english, 2016

6

Effect of triptolide on estradiol release from cultured rat granulosa cells

Zhang, Juan, Liu, Li, Mu, Xianmin, Jiang, Zhenzhou, Zhang, Luyong

Journal:

Endocrine Journal

Year:

2012

Language:

english

File:

PDF, 920 KB

english, 2012

7

In�vivo acquired sorafenib‑resistant patient‑derived tumor model displays alternative angiogenic pathways, multi‑drug resistance and chromosome instability

Hu, Gang, Zhang, Yixin, Ouyang, Kedong, Xie, Fubo, Fang, Houshun, Yang, Xueyang, Liu, Kunyan, Wang, Zongyu, Tang, Xuzhen, Liu, Jibin, Yang, Lei, Jiang, Zhenzhou, Tao, Weikang, Zhou, He, Zhang, Luyong

Journal:

Oncology Letters

Year:

2018

Language:

english

File:

PDF, 1.17 MB

english, 2018

8

A potential therapeutic effect of catalpol in Duchenne muscular dystrophy revealed by binding with TAK1

Xu, Dengqiu, Zhao, Lei, Jiang, Jingwei, Li, Sijia, Sun, Zeren, Huang, Xiaofei, Li, Chunjie, Wang, Tao, Sun, Lixin, Li, Xihua, Jiang, Zhenzhou, Zhang, Luyong

Journal:

Journal of Cachexia, Sarcopenia and Muscle

Year:

2020

File:

PDF, 25.43 MB

2020

9

Stabilization of a β-Hairpin Conformation in a Cyclic Peptide Using the Templating Effect of a Heterochiral Diproline Unit

Julia Späth, Fiona Stuart, Luyong Jiang, John A. Robinson

Journal:

Helvetica Chimica Acta

Year:

1998

Language:

english

File:

PDF, 313 KB

english, 1998

10

Cover Picture

Rafael Moreno, Luyong Jiang, Kerstin Moehle, Rinaldo Zurbriggen, Reinhard Glück, John A. Robinson, Gerd Pluschke

Journal:

Year:

2001

Language:

english

File:

PDF, 39 KB

english, 2001

11

Exploiting Conformationally Constrained Peptidomimetics and an Efficient Human-Compatible Delivery System in Synthetic Vaccine Design

Rafael Moreno, Luyong Jiang, Kerstin Moehle, Rinaldo Zurbriggen, Reinhard Glück, John A. Robinson, Gerd Pluschke

Journal:

Year:

2001

Language:

english

File:

PDF, 129 KB

english, 2001

12

Exploiting Conformationally Constrained Peptidomimetics and an Efficient Human-Compatible Delivery System in Synthetic Vaccine Design

Rafael Moreno, Luyong Jiang, Kerstin Moehle, Rinaldo Zurbriggen, Reinhard Glück, John A. Robinson, Gerd Pluschke

Journal:

Year:

2002

Language:

english

File:

PDF, 39 KB

english, 2002

13

Simultaneous determination of ZLR-8 and its active metabolite diclofenac in dog plasma by high-performance liquid chromatography

Haoyan Jiao, Fengguo Xu, Zunjian Zhang, Yuan Tian, Zhenzhou Jiang, Luyong Zhang

Journal:

Biomedical Chromatography

Year:

2007

Language:

english

File:

PDF, 183 KB

english, 2007

14

ChemInform Abstract: The Supramolecular Chemistry of Proteins—Protein Epitope Mimetics Prepared Using Combinatorial Biomimetic Chemistry

Luyong Jiang, Michel Favre, Kerstin Moehle, John A. Robinson

Journal:

Year:

2001

File:

PDF, 25 KB

2001

15

ChemInform Abstract: Exploiting Conformationally Constrained Peptidomimetics and an Efficient Human-Compatible Delivery System in Synthetic Vaccine Design.

Rafael Moreno, Luyong Jiang, Kerstin Moehle, Rinaldo Zurbriggen, Reinhard Glueck, John A. Robinson, Gerd Pluschke

Journal:

Year:

2002

File:

PDF, 26 KB

2002

16

Prevention of free fatty acid–induced hepatic lipotoxicity by 18β-glycyrrhetinic acid through lysosomal and mitochondrial pathways

Xudong Wu, Luyong Zhang, Emily Gurley, Elaine Studer, Jing Shang, Tao Wang, Cuifen Wang, Ming Yan, Zhenzhou Jiang, Phillip B. Hylemon, Arun J. Sanyal, William M. Pandak Jr, Huiping Zhou

Journal:

Year:

2008

Language:

english

File:

PDF, 2.17 MB

english, 2008

17

Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme

Ling Chen, Honglin Li, Jun Liu, Luyong Zhang, Hong Liu, Hualiang Jiang

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 976 KB

english, 2007

18

Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats

Li Liu, Zhenzhou Jiang, Jing Liu, Xin Huang, Tao Wang, Jun Liu, Yun Zhang, Zhixing Zhou, Jianlu Guo, Lina Yang, Yun Chen, Luyong Zhang

Journal:

Year:

2010

Language:

english

File:

PDF, 1008 KB

english, 2010

19

Fluorinated and iodinated templates for syntheses of β-turn peptidomimetics

Luyong Jiang, Kevin Burgess

Journal:

Year:

2002

Language:

english

File:

PDF, 601 KB

english, 2002

20

Preclinical anti-angiogenesis and anti-tumor activity of SIM010603, an oral, multi-targets receptor tyrosine kinases inhibitor

Dongchun Wang, Feng Tang, Sen Wang, Zhenzhou Jiang, Luyong Zhang

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 563 KB

english, 2012

21

A sensitive and specific liquid chromatography–mass spectrometry method for determination of metacavir in rat plasma

Zhan Li, Xin Huang, Zhenzhou Jiang, Yajie Xiao, Chunhui Liu, Luyong Zhang, Bin Shu, Jingfeng Huang, Tao Li, Tao Wang, Feng Wang

Journal:

Journal of Chromatography B

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

22

Application of a Novel Design Paradigm to Generate General Nonpeptide Combinatorial Templates Mimicking β-Turns: Synthesis of Ligands for Melanocortin Receptors

Webb, Thomas R., Jiang, Luyong, Sviridov, Sergey, Venegas, Ruben E., Vlaskina, Anna V., McGrath, Douglas, Tucker, John, Wang, Jian, Deschenes, Alain, Li, Rongshi

Journal:

Journal of Combinatorial Chemistry

Year:

2007

Language:

english

File:

PDF, 105 KB

english, 2007

23

Simultaneous determination of metacavir and its metabolites in rat plasma using high-performance liquid chromatography with tandem mass spectrometric detection (LC-MS/MS)

Yue Zhang, Xin Huang, Zhenzhou Jiang, Xiao Huang, Yue Hu, Dan Zhu, Shuang Zhang, Jiaying Wang, Luyong Zhang

Journal:

Biomedical Chromatography

Year:

2012

Language:

english

File:

PDF, 351 KB

english, 2012

24

Gene expression profiling reveals potential key pathways involved in pyrazinamide-mediated hepatotoxicity in Wistar rats

Yun Zhang, Zhenzhou Jiang, Yijing Su, Mi Chen, Fu Li, Li Liu, Lixin Sun, Yun Wang, Shuang Zhang, Luyong Zhang

Journal:

Journal of Applied Toxicology

Year:

2012

Language:

english

File:

PDF, 2.25 MB

english, 2012

25

Concurrent and sequential administration of sunitinib malate and docetaxel in human non-small cell lung cancer cells and xenografts

Dongchun Wang, Zhenzhou Jiang, Luyong Zhang

Journal:

Medical Oncology

Year:

2012

Language:

english

File:

PDF, 337 KB

english, 2012

26

Inhibition of mitochondrial respiratory chain is involved in triptolide-induced liver injury

Qiang Fu, Xiao Huang, Bin Shu, Mei Xue, Pinghu Zhang, Tao Wang, Li Liu, Zhenzhou Jiang, Luyong Zhang

Journal:

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

27

Effects of triptolide from Tripterygium wilfordii on ERα and p53 expression in two human breast cancer cell lines

Jing Liu, Zhenzhou Jiang, Jingwei Xiao, Yun Zhang, Sensen Lin, Weigang Duan, Jincheng Yao, Chunhui Liu, Xin Huang, Tao Wang, Zhongliang Liang, Rongrong Wang, Shuang Zhang, Luyong Zhang

Journal:

Year:

2009

Language:

english

File:

PDF, 788 KB

english, 2009

28

Identification of NME5 as a contributor to innate resistance to gemcitabine in pancreatic cancer cells

Fu Li, Gang Hu, Zhenzhou Jiang, Jingjing Guo, Ke Wang, Kedong Ouyang, Danyi Wen, Minghua Zhu, Jiaxin Liang, Xiaoran Qin, Luyong Zhang

Journal:

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012

29

On the importance of being aromatic at an antibody-protein antigen interface: mutagenesis of the extracellular interferon γ receptor and recognition by the neutralizing antibody A6

Klaus Hofstädter, Fiona Stuart, Luyong Jiang, Jan W Vrijbloed, John A Robinson

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 316 KB

english, 1999

30

Inhibition of aquaporin-1 expression by RNAi protects against aristolochic acid I-induced apoptosis in human proximal tubular epithelial (HK-2) cells

Liang Zhang, Ji Li, ZhenZhou Jiang, LiXin Sun, Xue Mei, Bian Yong, LuYong Zhang

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 847 KB

english, 2011

31

Triptolide inhibits COX-2 expression by regulating mRNA stability in TNF-α-treated A549 cells

Lixin Sun, Shuang Zhang, Zhenzhou Jiang, Xin Huang, Tao Wang, Xiao Huang, Han Li, Luyong Zhang

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 800 KB

english, 2011

32

Transactivation of the human NME5 gene by Sp1 in pancreatic cancer cells

Fu Li, Zhenzhou Jiang, Ke Wang, Jingjing Guo, Gang Hu, Lixin Sun, Tao Wang, Xuzhen Tang, Ling He, Jincheng Yao, Danyi Wen, Xiaoran Qin, Luyong Zhang

Journal:

Year:

2012

Language:

english

File:

PDF, 887 KB

english, 2012

33

Caspase 3 is involved in the apoptosis induced by triptolide in HK-2 cells

Bin Shu, Weigang Duan, Jincheng Yao, Jingfeng Huang, Zhenzhou Jiang, Luyong Zhang

Journal:

Toxicology in Vitro

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

34

Toxicities of aristolochic acid I and aristololactam I in cultured renal epithelial cells

Ji Li, Liang Zhang, Zhenzhou Jiang, Bin Shu, Fu Li, Qingli Bao, Luyong Zhang

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

35

Simultaneous determination of three flavonoid C-glycosides in mice biosamples by HPLC–ESI-MS method after oral administration of Abrus mollis extract and its application to biodistribution studies

Hao Wang, Zhenzhou Jiang, Huibing Du, Chunyi Liang, Yuanchao Wang, Mohan Zhang, Luyong Zhang, Wencai Ye, Ping Li

Journal:

Journal of Chromatography B

Year:

2012

Language:

english

File:

PDF, 893 KB

english, 2012

36

The furano norclerodane diterpenoid disobulbin-D induces apoptosis in normal human liver L-02 cells

Min Ma, Zhenzhou Jiang, Jinlan Ruan, Xinqi Tan, Jin Liu, Cuifen Wang, Xiao Ming Zha, Luyong Zhang

Journal:

Experimental and Toxicologic Pathology

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

37

Participation of cathepsin B in emodin-induced apoptosis in HK-2 Cells

Cuifen Wang, Zhenzhou Jiang, Jincheng Yao, Xudong Wu, Li Sun, Chunhui Liu, Weigang Duan, Ming Yan, Lixin Sun, Jun Liu, Luyong Zhang

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 1.80 MB

english, 2008

38

Pristimerin, a Triterpenoid, Inhibits Tumor Angiogenesis by Targeting VEGFR2 Activation

Mu, Xianmin, Shi, Wei, Sun, Lixin, Li, Han, Jiang, Zhenzhou, Zhang, Luyong

Journal:

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

39

Gene expression profiling and pathway analysis of hepatotoxicity induced by triptolide in Wistar rats

Wang, Jiaying, Jiang, Zhenzhou, Ji, Jinzi, Wang, Xinzhi, Wang, Tao, Zhang, Yun, Tai, Ting, Chen, Mi, Sun, Lixin, Li, Xia, Zhang, Luyong

Journal:

Food and Chemical Toxicology

Year:

2013

Language:

english

File:

PDF, 2.22 MB

english, 2013

40

Triptolide induces adverse effect on reproductive parameters of female Sprague-Dawley rats

Liu, Jing, Jiang, Zhenzhou, Liu, Li, Zhang, Yun, Zhang, Shuang, Xiao, Jingwei, Ma, Min, Zhang, Luyong

Journal:

Drug and Chemical Toxicology

Year:

2011

Language:

english

File:

PDF, 842 KB

english, 2011

41

Triptolide alters barrier function in renal proximal tubular cells in rats

Sun, Lixin, Li, Han, Huang, Xin, Wang, Tao, Zhang, Shuang, Yang, Jing, Huang, Shan, Mei, Huifang, Jiang, Zhenzhou, Zhang, Luyong

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 2.18 MB

english, 2013

42

proNGF inhibits proliferation and oligodendrogenesis of postnatal hippocampal neural stem/progenitor cells through p75NTR in vitro

Guo, Jingjing, Wang, Jianing, Liang, Chunrong, Yan, Jun, Wang, Yeran, Liu, Gaoxiang, Jiang, Zhenzhou, Zhang, Luyong, Wang, Xiaobin, Wang, Yanjiang, Zhou, Xinfu, Liao, Hong

Journal:

Stem Cell Research

Year:

2013

Language:

english

File:

PDF, 2.43 MB

english, 2013

43

Possible role of mtDNA depletion and respiratory chain defects in aristolochic acid I-induced acute nephrotoxicity

Jiang, Zhenzhou, Bao, Qingli, Sun, Lixin, Huang, Xin, Wang, Tao, Zhang, Shuang, Li, Han, Zhang, Luyong

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

44

Th17/Treg imbalance in triptolide-induced liver injury

Wang, Xinzhi, Jiang, Zhenzhou, Cao, Weiping, Yuan, Ziqiao, Sun, LiXin, Zhang, Luyong

Journal:

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

45

Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects

Jiang, Zhenzhou, Wu, Meijuan, Miao, Jingshan, Duan, Huaqin, Zhang, Shuang, Chen, Mi, Sun, Lixin, Wang, Yurong, Zhang, Xueji, Zhu, Xiong, Zhang, Luyong

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 3.48 MB

english, 2013

46

Deoxypodophyllotoxin triggers necroptosis in human non-small cell lung cancer NCI-H460 cells

Wu, Meijuan, Jiang, Zhenzhou, Duan, Huaqin, Sun, Lixin, Zhang, Shuang, Chen, Mi, Wang, Yun, Gao, Qin, Song, Yuming, Zhu, Xiong, Zhang, Luyong

Journal:

Biomedicine & Pharmacotherapy

Year:

2013

Language:

english

File:

PDF, 1.41 MB

english, 2013

47

A rapid and sensitive LC–ESI-MS/MS method for the detection of YF-49–92.MLS in rat plasma

Gao, Qin, Huang, Xin, Jiang, Zhenzhou, Liu, Guanlan, Xiao, Yi, Sun, Lixin, Wang, Tao, Zhang, Luyong, Xie, Shaofei, Huang, Haiyan

Journal:

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

48

Interleukin-17 mediates triptolide-induced liver injury in mice

Wang, Xinzhi, Jiang, Zhenzhou, Xing, Mengtao, Fu, Jing, Su, Yuwen, Sun, Lixin, Zhang, Luyong

Journal:

Food and Chemical Toxicology

Year:

2014

Language:

english

File:

PDF, 3.79 MB

english, 2014

49

KU004 induces G1 cell cycle arrest in human breast cancer SKBR-3 cells by modulating PI3K/Akt pathway

Fu, Jing, Tian, Chongchong, Xing, Mengtao, Wang, Xinzhi, Guo, Hongli, Sun, Lixin, Sun, Lan, Jiang, Zhenzhou, Zhang, Luyong

Journal:

Biomedicine & Pharmacotherapy

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

50

Oxidative Induction of β-Turn Conformations in Cyclic Peptidomimetics: Conformational Analyses As Indicators of Configuration

Jiang, Luyong, Burgess, Kevin

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 81 KB

english, 2002

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